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Symposium S.A1 - Myeloid lineage specification

Monday, September 3, 2018; 08:30-09:45

Chairpersons: William Agace, Denmark & Ed Lavelle, Ireland

Muzlifah Haniffa, United Kingdom
Consequences of antigen presenting cell networks in the skin

Ido Amit, Israel
The power of ONE: Immunology in the the age of single cell genomics

Martin Guilliams, Belgium
The macrophage niche: in search of the tissue-specific signals controlling macrophage development










Symposium S.A2 - Immune development and aging from the cradle to the grave

Monday, September 3, 2018; 14:45-16:00

Chairpersons: Nuno Alves, Portugal & Ricardo Pujol-Borrel, Spain

Hans Reimer Rodewald, Germany
Dissecting blood and immune cell lineages by endogenous barcoding

Kai Kisand, Estonia
Central tolerance - implications from monogenic autoimmunity

Arne Akbar, United Kingdom
Strategies for enhancing human immunity during ageing










Symposium S.A3 - Immunomonitoring and biomarkers

Monday, September 3, 2018; 16:30-17:45

Chairpersons: Christine Falk, Germany & Barbaros Oral, Turkey

Peter Openshaw, United Kingdom
Protective vaccination against respiratory viruses

Marianne van Hage, Sweden
Biomarkers for allergen-specific immunotherapy

Tomas Kalina, Czech Republic
Cytometry, immunmonitoring










Symposium S.A4 - Germinal centers and B cell differentiation

Tuesday, September 4, 2018; 08:30-09:45

Chairpersons: Marieke van Ham, The Netherlands & Jürgen Wienands, Germany

Robert Brink, Australia
Germinal centers under the lens; control of B cell differentiation by antigen
and follicular Thelper cells

Karin Tarte, France
Microenvironment in B-cell lymphomas: friend or foe?

Theo Rispens, The Netherlands










Symposium S.A5 - Initiation of immune responses

Tuesday, September 4, 2018; 14:45-16:00

Chairpersons: Anna Erdei, Hungary & Alexandra Tsirogianni, Greece

Greta Guarda, Switzerland
Regulation of cytotoxic responses

Theo Geijtenbeek, The Netherlands
Dendritic cells in HIV-1 sensing and restriction

Marina Botto, United Kingdom
The role of Complement in Tolerance










Symposium S.A6 - Lessons learned from the genetic defects

Tuesday, September 4, 2018; 16:30-17:45

Chairpersons: Günnur Deniz, Turkey & Hilary Longhurst, United Kingdom

Ahmet Ozen, Turkey
Early onset protein losing enteropathy and thrombosis in inherited CD55 deficiency

Anne Puel, France
Primary immunodeficiances

Kaan Boztug, Austria
Novel Monogenic Causes of Immune Dysregulation










(c) MedUni Vienna/Matern


Symposium S.B1 - Tumor vaccination principles and immuno therapy

Monday, September 3, 2018; 08:30-09:45

Chairpersons: Silke Appel, Norway & Blanka Rihova, Czech Republic

Johanna Olweus, Norway
Donor-derived T-cell receptors in cancer immunotherapy

Eric Vivier, France
Next generation Immunotherapies











Symposium S.B2 - Environmental regulation anti-tumor responses

Monday, September 3, 2018; 16:30-17:45

Chairpersons: Ignacio Melero, Spain & Vito Pistoia, Italy

Vincenzo Bronte, Italy
"Flipping" over monocytes into immune regulatory cells

Angel Porgador, Israel
Splice variant-based immune checkpoints for NK in the cancer microenvironment

Karin de Visser, The Netherlands
Dissecting immune complexity of metastatic breast cancer










Symposium S.B3 - The Yin and Yang of T-cell regulation

Tuesday, September 4, 2018; 08:30-09:45

Chairpersons: Friederike Berberich-Siebelt, Germany & Hans Yssel, France

Alexander Scheffold, Germany
Antigen-specific regulatory T cells in human immunity

Jannie Borst, The Netherlands
How help for the CTL response generates robust antitumor immunity

Lucy Walker, United Kingdom
Maintaining T cell tolerance via the CTLA-4 pathway










Symposium S.B4 - T cell activation and exhaustion

Wednesday, September 5, 2018; 12:00-13:15

Chairpersons: Michael Lohoff, Germany & Shohreh Issazadeh-Navikas, Denmark

Ton Schumacher, The Netherlands
T cell heterogeneity in human cancer

Sven Kracker, France
Immunodeficiencies associated with increased T cell senescence

Dietmar Zehn, Germany
Maintenance of “exhausted” T cells in chronic infection










Symposium S.C1 - Maintenance and local regulation of tissue specific immunity

Sunday, September 2, 2018; 16:30-17:45

Chairpersons: Muzlifa Haniffa, United Kingdom & Percy Knolle, Germany

Tobias Bopp, Germany
Context- and Mucosa-specific Regulation of Immunity and Tolerance by Regulatory T Cells

David Masopust, United States
Functions of Resident Memory T Cells

Francesca Granucci, Italy
Activation of Ca2+ regulated pathways downstream of Pattern Recognition Receptors










Symposium S.C2 - Immune signalling and therapy in autoimmunity

Monday, September 3, 2018; 14:45-16:00

Chairpersons: Ed Geissler, Germany & Güher Saruhan-Direskeneli, Turkey

Trevor Owens, Denmark
Myeloid and glial cells collaborate to regulate neuroinflammation

Attila Mocsai, Hungary
Intracellular signaling during autoimmune inflammation

David Wraith, United Kingdom
How to modulate TCR signalling for peptide therapy in autoimmunity










Symposium S.C3 - Transplantation

Tuesday, September 4, 2018; 14:45-16:00

Chairpersons: David Wraith, United Kingdom & Oliver Papst, Germany

Piotr Trzonkowski, Poland
Treating autoimmune diseases with T regulatory cells – first clinical data

Mette Hazenberg, The Netherlands
Innate lymphoid cells and microbioma in GvHD

Chiara Bonini, Italy
Transplantation, T cell engineering










Symposium S.C4 - Manipulation of tolerance

Tuesday, September 4, 2018; 16:30-17:45

Chairpersons: Anja ten Brinke, The Netherlands & Anna Sediva, Czech Republic

Silvia Gregori, Italy
Engineered Dendritic Cells to re-establish Antigen-Specific Tolerance in T-cell Mediated Diseases

Benoit Salomon, France
The role of cell metabolism in Treg biology and function

Eva Martínez Caceres, Spain
Tolerogenic dendritic cells as therapeutic strategy to induce tolerance in MS










Symposium S.C5 - Allergy, asthma and therapy

Wednesday, September 5, 2018; 08:30-09:45

Chairpersons: Clare Lloyd, United Kingdom & Rudolf Valenta, Austria

Bart Lambrecht, Belgium
Spontaneous protein crystallization in asthma: A new pathway for intervention

Jürgen Wienands, Germany
Isotype-specific regulation of BCR signal transduction

Winfried Pickl, Austria
Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice










Symposium S.C6 - Innate control of inflammation and tissue repair

Wednesday, September 4, 2018; 13:45-15:00

Chairpersons: Vèronique Witko-Sarsat, France & Zsolt Szepfalusi, Austria

Alberto Mantovani, Italy
The yin yang of phagocyte regulation and inflammatory cytokines

Hans-Uwe Simon, Switzerland
Extracellular DNA traps: Neutrophils, eosinophils, basophils

Pablo Pelegrin Vivancos, Spain
Mitochondrial failure in monocytes immunocompromise the NLRP3 inflammasome in human sepsis










Symposium S.D1 - Microbiome, metabolites and the immune system

Monday, September 3, 2018; 14:45-16:00

Chairpersons: Gerd Bouma, The Netherlands & Arno Hänninen, Finland

Kevin Maloy, United Kingdom
Autophagy regulates chronic intestinal inflammation at several levels

Oliver Pabst, Germany
Antibody responses to the intestinal microbiota

Janneke Samsom, The Netherlands
Regulating intestinal immune responses to luminal antigens










Symposium S.D2 - Innate lymphoid cells - a topic of debate

Monday, September 3, 2018; 16:30-17:45

Chairpersons: Andreas Diefenbach, Germany & Adrian Hayday, United Kingdom

Dan Davis, United Kingdom
Using super-resolution microscopy to watch immune cells kill

James di Santo and Chiara Romagnani, France/Germany (Pro & Con lecture)
Human Innate Lymphoid cells










Symposium S.D3 - Novel approaches to vaccinology

Tuesday, September 4, 2018; 14:45-16:00

Chairpersons: Africa Gonzàlez-Fernàndez, Spain & Peter Openshaw, United Kingdom

Sarah Gilbert, United Kingdom
Viral vaccine delivery systems

Florian Klein, Germany
Broadly neutralizing antibodies targeting HIV-1

Antonio Lanzavecchia, Switzerland
Therapeutic monoclonal antibodies










Symposium S.D4 - Exploiting host pathogen interaction

Wednesday, September 5, 2018; 12:00-13:15

Chairpersons: Jaap van Dissel, The Netherlands & Gary Entrican, United Kingdom

David Holden, United Kingdom
Immune suppression by Salmonella

Nikos Papadopoulous, Greece
Immune deviations in virus-induced asthma

Kathy McCoy, Canada
Microbial regulation of innate immunity and homeostasis












Symposium S.E1 - Visualizing immune responses

Sunday, September 2, 2018; 16:30-17:45

Chairpersons: Burkhard Ludewig, Switzerland & Reina Mebius, The Netherlands

Gillian Griffith, United Kingdom
Cancer assassins:  the secrets of serial killers

Henrique Veiga Fernandez, Portugal
Innate lymphoid cells and the second brain

Matteo Iannacone, Italy
In vivo imaging of antiviral immune responses










Symposium S.E2 - How to handle big data and can we do this?

Tuesday, September 4, 2018; 16:30-17:45

Chairpersons: Angela Santoni, Italy & Thomas Kamradt, Germany

Jacques Neefjes, The Netherlands
Does big data-mining help in understanding MHC class II antigen presentation?

Joachim Schultze and Rolf Zinkernagel, Germany/Switzerland (Pro & Con session)
How to make sense out of big data in immunology: The single cell genomics revolution as an example










Symposium S.E3 - From single cells to population dynamics

Wednesday, September 5, 2018; 08:30-09:45

Chairpersons: Frits Koning, The Netherlands & Valentina Proserpio, Italy

Jenny Mjösberg, Sweden
Human innate lymphoid cells in health and disease

Dirk Busch, Germany
Characterization of T cell responses by single cell in vivo fate mapping

Birgit Sawitzki, Germany
Standardized multi-parametric immune profiling to predict outcome of inflammatory diseases










Symposium S.E4 - Cell communication and signaling in the immune system

Wednesday, September 5, 2018; 13:45-15:00

Chairpersons: Francisco Sanchez-Madrid, Spain & Odmund Bakke, Norway

Clotilde Thery, France
Common and distinct Immune functions of exosomes and other extracellular vesicles

Michael Dustin, United Kingdom
Flexibility in immune synapse compartmentalisation changes set point for T cell responses

Tim Sparwasser, Germany
Influencing immune cell activation and differentiation by microbe-associated immunomodulatory metabolites