Keynote lecture 1: SERENDIPITIES OF ACQUIRED IMMUNITY
Sunday, September 2, 2018; 15:30-16:15
Chairpersons: Barbara Bohle, Austria & Cornelius Melief, The Netherlands
Dr. Honjo is well known for his discovery of activation-induced cytidine deaminase that is essential for class switch recombination and somatic hypermutation. He has established the basic conceptual framework of class switch recombination. In addition, he discovered PD-1 (program cell death 1), a negative coreceptor at the effector phase of immune response and showed that PD-1 modulation contributes to treatments of tumor, viral infection and autoimmunity. For these contributions, Dr. Honjo has received many awards, including Imperial Prize, Japan Academy Prize, Robert Koch Prize, Order of Culture, the Tang Prize, William B. Coley Award, Richard V. Smalley, MD Memorial Award, the Kyoto Prize, the Keio Medical Science Prize, Warren Alpert Foundation Prize and Japan Bioindustry Award. Elected as a foreign associate of National Academy of Sciences, USA, as a member of the German Academy of Natural Scientists, and also as a member of Japan Academy.